About 1 result found for searched term "DSM705 hydrochloride " (0.128 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M31056 | DSM705 hydrochloride | DHODH |
| DSM705 hydrochloride, an orally active antimalarial compound, is a pyrrole-based Dihydroorotate Dehydrogenase (DHODH) inhibitor. DSM705 hydrochloride exhibits nanomolar potency against Plasmodium DHODH and Plasmodium parasites (IC50=95, 52 nM for P. falciparum and P. vivax DHODH, respectively), with no inhibition of mammalian DHODHs. | ||
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